Figure 2
From: Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human In Vitro Systems

Hydrolysis of amides by human carboxylesterase Supersomes. Compounds labelled I are hydrolysed in humans, II are not hydrolysed in humans and III have unknown human in vivo metabolism. 4-Br-NPB and 2-Cl-NPA represent 4-bromo-2-methoxy-N-phenylbenzamide and 2-chloro-N-phenylacetamide.