Table 1 Characteristics of included studies.

From: The risk of cognitive impairment associated with hearing function in older adults: a pooled analysis of data from eleven studies

Studies

Country (Ethnicity)

Mean age at baseline (SD)

Participant numbers

Female (%)

Event numbers

Maximum follow-up years

Hearing function evaluations

Instruments qualifying/quantifying cognitive status

Deal JA29

US (White and Black)

75.5 (3.0)

1,889

52.7

229

9

Pure-tone audiometry

3MS score

Fritze T32

Germany (NA)

 ≥ 65

154,783

NA

14,602

6

ICD-10

ICD-10

Gates GA31

US (NA)

72 (63–95)a

1,662/1,026b

60.2

41

6

Pure-tone audiometry, SSI-ICM

MMSE score

Gates GA30

US (NA)

79.6 (5.2)

274

62.8

21

2.2 (0.8–4)a

SSI-ICM

CASI score, DSM-IV, and NINCDS-ADRDA

Gurgel RK33

US (NA)

75.5 (6.9)

4,463

60

574

5.8 (4.2)c

Self-report interview

3MS score, DSM-III-R, and NINCDS-ADRDA

Hong T24

Australia (NA)

68.2 (7.9)d

1,638d

43.7d

NA

10

Pure-tone audiometry

MMSE blind

Karpa MJ9

Australia (NA)

66.6 (9.3)

2,815

56.7

NA

9

Pure-tone audiometry

MMSE score

Lin FR14

US (Black, White and other)

63.6 (12.8)

639

43.7

58

11.9e

Pure-tone audiometry

DSM-III-R, and NINCDS-ADRDA

Lin FR20

US (White and Black)

77.4 (2.8)f

1,626

52.1f

609

6

Pure-tone audiometry

3MS score

Lin MY21

US (Black excluded)

76.1 (NA)

5,345

100

NA

4.4 (NA)c

Pure-tone audiometry

3MS score

Lyu J34

South Korea (Asian)

71.1 (4.9)

1,759

52.6

501

6

Self-report

Korean MMSE

  1. Abbreviations: 3MS = Modified Mini-Mental State Examination, CASI = Cognitive Abilities Screening Instrument, DSM = Diagnostic and Statistical Manual, ICD = International Classification of Diseases, MMSE = Mini-Mental State Examination, NA = not available, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association, SD = standard deviation, SSI-ICM = Synthetic Sentence Identification with Ipsilateral Competing Message, UK = United Kingdom, US = United States. aMean (range), bperipheral hearing test/central hearing test, cmean (SD), ddata from hearing impairment cohort and controls, emedian, fdata from the whole cohort.