Table 1 Summary of the N-glycan structures seen in the crystal structures of AOC3 published to date. HEK293 = Human embryonic kidney cells; residues 29–763; CHO1 = Chinese hamster ovary cells; residues 1–763; CHO2 = Chinese hamster ovary cells; 34–763; NAG = N-acetyl-beta-D-glucosamine; BMA = beta-D-mannose; MAN = alpha-D-mannose; NDG = N-acetyl-alpha-D-glucosamine; FUC = alpha-L-fucose; FUL = beta-L-fucose. aNot linked to the rest of the glycan.
ID | Res./Å | Source | N137 | N232 | N294 | N592 | N618 | N666 | Reference |
|---|---|---|---|---|---|---|---|---|---|
4BTW:A | 2.8 | Human serum | NAG-NAG-BMA | NAG-NAG | NAG | NAG | |||
4BTW:B | 2.8 | Human serum | NAG-NAG-BMA-MAN-BMA | NAG-NAG | NAG | NAG | NAG | ||
4BTY:A | 3.1 | Human serum | NAG-NAG | NAG | NAG | NAG | |||
4BTY:B | 3.1 | Human serum | NAG-NAG-BMA-MAN-MAN | NAG-NAG | NAG | ||||
4BTX:A | 2.78 | Human serum | NAG-NAG-BMA | NAG | NAG | ||||
4BTX:B | 2.78 | Human serum | NAG-NAG-MAN | NAG | NAG | NAG | NAG | NAG | |
2Y73:A | 2.6 | Human serum | NAG-NAG-MAN | NAG-NAG | NAG | NAG | |||
2Y73:B | 2.6 | Human serum | NAG-NAG-MAN | NAG-NAG | NAG | NAG | |||
2Y74:A | 2.95 | Human serum | NAG-NAG-MAN | NAG-NAG | NAG | NAG | |||
2Y74:B | 2.95 | Human serum | NAG-NAG-MAN | NAG-NAG | NAG | NAG | |||
2C10:A | 2.5 | HEK293 | NAG-NAG-BMA | NAG | NAG | NGD | |||
2C10:B | 2.5 | HEK293 | NAG-NAG-BMA | NAG-NAG | NAG | NGD-FUL-NAG-BMA-MAN NAGa | NAG | ||
2C10:C | 2.5 | HEK293 | NAG-NAG-BMA | NAG-NAG | NAG | NGD-FUL-FUL | |||
2C10:D | 2.5 | HEK293 | NAG-NAG-BMA-MAN | NAG-NAG | NAG | NGD-FUL-NAG-BMA-MAN | NAG | ||
2C11:A | 2.9 | HEK293 | NAG-NAG | NAG | NAG | NAG-FUL | |||
2C11:B | 2.9 | HEK293 | NAG-NAG-BMA | NAG | NAG | NGD-FUL-NAG-BMA-MAN | NAG | ||
2C11:C | 2.9 | HEK293 | NAG-NAG | NAG | NAG | NAG-FUL-NAG | |||
2C11:D | 2.9 | HEK293 | NAG-NAG-BMA | NAG | NAG | NGD-FUL-NAG-BMA-MAN | NAG | ||
1US1:A | 2.9 | CHO | NAG-NAG | NAG | |||||
1US1:B | 2.9 | CHO | NAG-NAG | NAG | |||||
1PU4:A | 3.2 | CHO | NAG-NAG | NAG | |||||
1PU4:B | 3.2 | CHO | NAG-NAG | NAG | |||||
3ALA:A | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NDG-FUL | ||||
3ALA:B | 2.9 | CHO | NAG-NAG-BMA | NAG | NAG-FUL-NAG | ||||
3ALA:C | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NAG-FUL | ||||
3ALA:D | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NAG-FUL | NAG | |||
3ALA:E | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NAG-FUL | ||||
3ALA:F | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NAG-FUL | ||||
3ALA:G | 2.9 | CHO | NAG-NAG-BMA | NAG-NAG | NAG-FUC |
