Figure 4

Hysteresis of patterning in deformation process. (a) Time series images of tissue patterning under the condition of activator-independent homogeneous cell growth. (b) Developed pattern without cell growth on the arrested tissue resulting from the simulation at t = 4.6 cell cycles in (a). (c) Regenerated pattern on the arrested tissue without cell growth, after homogenizing the molecular concentration at t = 4.6 cell cycles. In (a and b), cells are colored by their activator concentration. (d) Categorization of phenomena based on the difference in time scales between patterning and deformation. To obtain the tissues in (a), physical parameters were set as χ = 0.1. To obtain the tissues in (b,c), cell growth was arrested, and physical parameters were set as χ = 0.1.