Table 2 Clinical data of 21 patient suffering from severe TBI, and subsequently clinically diagnosed with DAI.
Case | Sex | Age | DAI grade (MRI scan) | GCS at admission | GOS at 6 months | Type of incident | Multiple or head trauma | Surgical procedure | MOF within 2 months | Hypotension | Survival (months) | Congo red, anti-β-APP, GFAP, IL-1β, NFL, Spectrin II, 8OHdG, TUNEL assay | miR-21, miR-92, miR-16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | 52 | 2 | 7 | 3 | Moto accident | Mainly Head | Craniectomy | No | No | Alive (35) | ||
2 | M | 16 | 2 | 6 | 2 | Car accident | Multiple Trauma | Shunting | No | No | Alive (54) | ||
3 | M | 28 | 2 | 5 | 2 | Violence | Multiple Trauma | Craniectomy | No | No | 9 | + | + |
4 | M | 39 | 3 | 5 | 2 | Car accident | Multiple Trauma | Craniectomy | Yes | No | 14 | + | + |
5 | M | 34 | 2 | 8 | 1 | Car accident | Mainly Head | Shunting | No | No | 4 | + | + |
6 | F | 54 | 3 | 3 | 1 | Car accident | Multiple Trauma | No | Yes | Yes | 0.1 | + | + |
7 | M | 25 | 3 | 4 | 1 | Moto accident | Multiple Trauma | Shunting | Yes | No | 0.5 | + | + |
8 | M | 69 | 3 | 3 | 1 | Car accident | Multiple Trauma | No | No | Yes | 2 | + | + |
9 | M | 37 | 2 | 4 | 2 | Car accident | Multiple Trauma | No | No | No | Alive (84) | ||
10 | M | 46 | 3 | 3 | 2 | Ran over | Mainly Head | Shunting | No | No | 8 | + | + |
11 | M | 50 | 1 | 7 | 4 | Car accident | Multiple Trauma | Craniectomy | No | No | Alive (24) | ||
12 | M | 72 | 3 | 3 | 1 | Precipitation | Mainly Head | No | Yes | Yes | 0.1 | + | + |
13 | M | 49 | 3 | 4 | 2 | Moto accident | Multiple Trauma | Craniectomy | No | No | 11 | + | + |
14 | M | 31 | 3 | 5 | 3 | Ran over | Multiple Trauma | Craniectomy | No | No | 18 | + | + |
15 | M | 44 | 3 | 5 | 1 | Car accident | Multiple Trauma | Shunting | Yes | No | 3 | + | + |
16 | F | 36 | 2 | 3 | 1 | Car accident | Multiple Trauma | No | No | Yes | 6 | + | + |
17 | M | 56 | 3 | 5 | 1 | Precipitation | Multiple Trauma | No | Yes | Yes | 0.5 | + | + |
18 | M | 25 | 3 | 5 | 3 | Moto accident | Multiple Trauma | No | No | No | 12 | + | + |
19 | M | 32 | 3 | 3 | 1 | Car accident | Multiple Trauma | Shunting | Yes | No | 0.5 | + | + |
20 | F | 19 | 3 | 4 | 1 | Moto accident | Multiple Trauma | Craniectomy | No | Yes | 1 | + | + |
21 | M | 15 | 2 | 8 | 4 | Moto accident | Mainly Head | Craniectomy | No | No | Alive (60) |
