Figure 2 | Scientific Reports

Figure 2

From: Neuroprotection of the hypoxic-ischemic mouse brain by human CD117+CD90+CD105+ amniotic fluid stem cells

Figure 2

SS-hAFSCs decrease hippocampal lesion and number of dead cells in hippocampus and striatum. (a) Quantification of brain tissue volume loss in contralateral forebrain, assessed by Nissl staining (Cresyl-Violet), showing reduction of infarct size in the hippocampus of HI mice injected with SS-hAFSCs (mean ± SEM), ***P < 0.001, * < 0.05. Representative images of Nissl-stained brain sections of HI mice injected with either PBS only, SS-hAFSCs or RS-hAFSCs. (b) TUNEL + staining showing reduced number of dying cells in HI brains injected with SS-hAFSCs. (mean ± SEM), **P < 0.01, *P < 0.05. Representative images (low and high magnification) of TUNEL-stained brain sections of HI mice injected with either PBS only, SS-hAFSCs or RS-hAFSCs.

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