Table 2 ATC groups most represented by drugs that target gene products of the top 25 modules.

From: Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

ATC group

ATC group code

Significant modules

n

ID

Antineoplastic and immunomodulating agents

L

13

18_4, 130_2, 134_1, 82_4, 171_2, 108_3, 137_2, 126_2, 143_5, 91_4, 116_1, 130_3, 124_1

Cardiovascular system

C

4

36_4, 17_3, 84_3, 72_6

Musculoskeletal system

M

4

17_3, 82_4, 163_1, 69_5

Blood and blood-forming organs

B

2

84_3, 10_3

Nervous system

N

1

124_1

Genitourinary system and sex hormones

G

1

130_3

Sensory organs

S

1

163_1

Alimentary tract and metabolism

A

0

 

Dermatologicals

D

0

 

Systemic hormonal preparations, excluding sex hormones and insulins

H

0

 

Anti-infectives for systemic use

J

0

 

Antiparasitic products, insecticides, and repellents

P

0

 

Respiratory system

R

0

 

Various

V

0

 
  1. Listed are the ATC groups and the number and IDs of the modules significantly enriched (Fisher’s exact test, right-tail P < 0.05) in targets of ATC drug groups. ATC, Anatomical Therapeutic Chemical Classification System.
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