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Figure 4

From: Epothilone B Speeds Corneal Nerve Regrowth and Functional Recovery through Microtubule Stabilization and Increased Nerve Beading

Figure 4

EpoB prevents axons from injury-induced degeneration at an early stage after corneal wounding. (A) Representative retraction bulbs in Zone 3, 5 h after abrasion (40X). (B) The number of retraction bulbs in Zone 3 in three groups at 5 h after abrasion (40X). (C) The nerve fragments in Zone 2 at 5 h after abrasion (40X). (D) The number of nerve-fractured fragments in Zone 2 in three groups at 5 h after abrasion (40X). Significant differences were found compared to the vehicle and normal groups (mean ± SD. Student’s t-test.) *P < 0.05, **P < 0.01, ***P < 0.001; n = 6 corneas/group.

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