Figure 6 | Scientific Reports

Figure 6

From: Epothilone B Speeds Corneal Nerve Regrowth and Functional Recovery through Microtubule Stabilization and Increased Nerve Beading

Figure 6

EpoB increases the beading frequency in Zone 3 of the corneal nerve fibers after injury. (A) Representative DeltaVision Elite high-resolution microscope images in Zone 3 showing beads in the normal control, vehicle control, and EpoB treatment groups at 6 days postinjury and in the uninjured group (bar = 10 μm, 40X). (B) The number of beads in Zone 3 in uninjured corneas and corneas from day 1 to day 6 after corneal abrasion. Significant differences were found compared to the vehicle and normal groups. The results are presented as the mean ± SD. A factorial design ANOVA was performed to analyze the overall differences between the two groups, and a Student’s t-test was used to compare the differences between the groups by time point. *P < 0.05, **P < 0.01; n = 6 corneas/group.

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