Figure 5 | Scientific Reports

Figure 5

From: Activated T follicular helper-like cells are released into blood after oral vaccination and correlate with vaccine specific mucosal B-cell memory

Figure 5

Oral ETEC vaccination induced increased expression of integrin β7 on activated cTfh cells and circulating plasmablasts. Expression of integrin β7 was analysed among activated cTfh cells (ICOS+CD4+CXCR5+) (a and b) and plasmablasts (CD27+CD38hiCD19+) (c and d) by FCM in PBMCs collected before (preVacc) and after (postVacc) vaccination. (a and c) Data pooled from the primary and booster vaccination study. Each symbol represents one individual (the same subjects as in Figs 1a–c and 2a). Bars indicate median values. (b and d) Representative stainings from one strong ALS responder.

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