Table 1 Inhibition of KB Cell Proliferation in vitro by Selected F-DANDYs.

From: DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives

Compound

% Growth inhibition 10−5 M

% Growth inhibition 10−6 M

5a

49 ± 3

0 ± 9

5c

22 ± 2

6 ± 2

5e

66 ± 3

30 ± 1

5 g

95 ± 1

46 ± 1

Back to article page