Figure 4 | Scientific Reports

Figure 4

From: In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density

Figure 4

(a) The depth dose (solid) and LETt (dashed) profile of an example proton SOBP with 2 Gy across the plateau comprised of nine pristine Bragg peaks. (b) The predictions of residual and misrepaired DSB yields for the same proton SOBP, calculated with equations (7) and (5) respectively. The ratio of residual DSBs to misrepaired DSBs is shown as a dashed line. The solid black vertical line on both graphs denotes the depth where the physical dose begins to fall off (15.58 cm).

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