Table 1 Magnetic resonance measures at 8 h and 28 h of fasting.

From: Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis

 

8 h

28 h

P value

Intra- and extramyocellular lipid

  Soleus

 SOL IMCL CH2/Cr

8.5 ± 1.0

10.7 ± 0.9

0.007

 SOL IMCL CH3/Cr

1.02 ± 0.12

1.14 ± 0.11

0.243

 SOL IMCL CH3:CH2

0.118 ± 0.004

0.106 ± 0.004

0.015

 SOL EMCL CH2/Cr

16.3 ± 2.3

16.6 ± 1.8

0.735

  Tibialis anterior

 TA IMCL CH2/Cr

4.2 ± 0.4

5.5 ± 0.4

 < 0.001

 TA IMCL CH3/Cr

0.77 ± 0.09

0.86 ± 0.07

0.033

 TA IMCL CH3:CH2

0.182 ± 0.011

0.157 ± 0.008

0.011

 TA EMCL CH2/Cr

10.2 ± 1.2

12.2 ± 1.6

0.157

Adipose tissue

SCATabd, cm3

781 ± 86

758 ± 81

0.012

VAT, cm3

336 ± 67

335 ± 69

0.650

SCATleg, cm2

13.1 ± 1.0

12.7 ± 1.0

0.001

IMF, cm2

2.4 ± 0.3

2.5 ± 0.2

0.274

Hepatic lipid

IHL CH2/water, %

0.91 ± 0.2

0.93 ± 0.2

0.082

  1. Data are mean ± SEM. Bold P values are statistically significant (p < 0.05), determined by a 2-tailed paired-samples t-test. IMCL, intramyocellular lipid; EMCL, extramyocellular lipid; SOL, soleus; TA, tibialis anterior; CH2/Cr, CH2 lipid expressed relative to the chosen internal standard creatine plus phosphocreatine (Cr); CH3/Cr, CH3 lipid expressed relative to Cr; CH3:CH2, CH3 lipid relative to CH2 lipid, used here as a marker of unsaturation; SCATabd, abdominal subcutaneous adipose tissue; VAT, visceral adipose tissue; SCATleg, leg subcutaneous adipose tissue; IMF, intermuscular fat; IHL, intrahepatic lipid. n = 19 and 22 in SOL and TA respectively.
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