Table 3 IBS-QOL scores: baseline to week 4.

From: The effect of Clostridium butyricum on symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial

 

IBS-QOL [Mean (SD)] and change from baseline [Mean (SD)]

Baseline

Week 4

Change from baseline

Placebo

CB

Placebo

CB

Placebo

CB

P value

QOL overall

82.88 (16.14)

81.28 (18.85)

86.04 (13.74)

88.51 (14.40)

3.159 (11.73)

7.232 (14.06)

0.032

Dysphoria

77.85 (23.08)

79.34 (23.88)

83.83 (18.64)

88.27 (19.06)

5.980 (16.22)

8.934 (17.67)

0.135

Activity interference

85.14 (17.83)

80.71 (20.86)

87.96 (13.81)

89.58 (14.86)

2.822 (13.34)

8.866 (15.81)

0.003

Body image

91.20 (15.99)

90.00 (16.49)

91.98 (13.08)

93.60 (11.33)

0.7716 (14.02)

3.603 (14.12)

0.072

Health worry

77.26 (20.83)

72.16 (23.34)

79.73 (20.49)

84.41 (20.32)

2.469 (16.43)

12.25 (18.03)

0.000

Food avoidance

68.31 (22.65)

65.39 (22.14)

72.94 (21.02)

72.84 (19.89)

4.630 (20.28)

7.451 (22.49)

0.381

Social reaction

87.35 (17.76)

86.84 (20.00)

87.96 (17.22)

91.69 (14.61)

0.6173 (10.44)

4.853 (16.38)

0.074

Sexual

90.28 (21.01)

86.62 (24.15)

91.36 (18.50)

91.76 (15.97)

1.080 (13.29)

5.147 (17.07)

0.119

Relationship

89.20 (19.38)

90.20 (16.82)

92.80 (15.91)

93.24 (12.76)

3.601 (13.88)

3.039 (13.96)

0.751