Figure 2

Computed tomography assessment and light micrographs. (a) At 0 weeks, no radiopacity was visible in the defect regions in the demineralised dentin matrix (DDM)-implanted and control groups. Over 12 weeks, the defect region showed increasing radiopacity in the DDM-implanted group. (b) The bone volume/total defect volume (BV/TV) increased incrementally. At 12 weeks, there was a significant difference. (c) The horizontal plane of the defect area in the DDM group at 12 weeks. (d) Higher magnification of the square area in panel (c). Newly formed bone tissue with the DDM as the core is visible in the haematoxylin and eosin stained sections from the DDM-implanted group. (e) A serial section of the image in (d). Solid red–purple matrices of the dentinal tubules are visible in the toluidine blue-stained sections.