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Figure 1

From: Microarray profile of circular RNAs identifies hsa_circ_0014130 as a new circular RNA biomarker in non-small cell lung cancer

Figure 1

Differences and characterizations of circRNA expression profile between NSCLC tissues and paired adjacent non-cancerous tissues. (A) Box plots show the distribution of circRNAs for the six samples (C for NSCLC and A for adjacent non-cancerous tissues). The distributions were nearly the same after normalization. (B) Unsupervised hierarchical clustering shows a distinguishable circRNA expression profiling among the six samples (C for NSCLC and A for adjacent non-cancerous tissues). Each column represents the expression profile of a tissue sample, and each row corresponds to a circRNA. “Red” indicates higher expression level, and “green” indicates lower expression level. (C) Volcano plots are used to visualize the differential circRNA expression. The vertical green lines correspond to 2.0-fold up and down, and the horizontal green line represents a P-value of 0.05. The red points in plot represent the differentially expressed circRNAs with statistical significance. (D) Chromosomal distributions of differentially expressed circRNAs.

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