Figure 4 | Scientific Reports

Figure 4

From: Microarray profile of circular RNAs identifies hsa_circ_0014130 as a new circular RNA biomarker in non-small cell lung cancer

Figure 4

The predicted hsa_circ_0014130 targeted circRNA-miRNA-mRNA gene co-expression network based on sequence-pairing prediction. (A) The co-expression network was drawn with the cytoscape software. Five miRNAs and their mRNA target genes were found with overlapping results. As shown in this figure, miR-216a-3p exhibited the largest interaction network followed by miR-302a-3p, miR-892a, miR-493-5p, and miR-200c-5p. (B) Seed sequence matching predicted the direct interaction of hsa_circRNA_0014130 with the three cancer-related miRNAs: miR-216a-3p, miR-493-5p and miR-200c-5p.

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