Figure 4
Effect of binge alcohol exposure on the spatial memory of adolescent rats. Adolescent rats received binge alcohol exposure for 4 days as described under the Materials and Methods. Three days after the last alcohol exposure, the rats were trained in the Morris water maze (MWM) and the learning ability and spatial memory were assessed. (A) The latency for finding the platform for each trial during the 5 day testing period was measured. (B) The swimming distance for finding the platform for each trial during the 5 day testing period was measured. All values are expressed as mean ± S.E.M. n = 10 for each group. *Indicates significant difference from the control group (p < 0.05). (C) The ratio of time spent in the target quadrant was determined. Data were presented as mean ± SEM; CT: 40.03 ± 3.02, ETOH: 30.13 ± 3.82 *p = 0.0398; (D) The time of crossing the platform was measured. Data were presented as mean ± SEM; CT: 1.375 ± 0.22, ETOH: 0.6875 ± 0.17 *p = 0.0212.
