Table 4 MS analysis of the ligation products between tryptophan analogs with typical amines.

From: A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism

Substrate for TycA-A

Nucleophile

l-Proline

Azetidine

Dimethylamine

6-Fluorotryptophan

320.1475

262.1401

250.1401

6-Chlorotryptophan

336.1170

278.1109

266.1119

6-Bromotryptophan

380.0649

322.0614

310.0617

5-Hydroxytryptophan

318.1503

260.1415

248.1448

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