Figure 3 | Scientific Reports

Figure 3

From: Lack of galectin-3 modifies differentially Notch ligands in bone marrow and spleen stromal cells interfering with B cell differentiation

Figure 3

Notch signaling pathway in the bone marrow of Lgals3−/− mice. Expression of the Notch signaling pathway components in total bone marrow cells of Lgals3+/+ (black bars) and Lgals3−/− mice (gray bars). The expression levels of JAG1 (A) DLL4 (B) ligands was measured in Lgals3+/+ and Lgals3−/− mice. Notch target transcription factors Hes-1 (C), Hey-1 (D), Hey-2 (E) and Hey-L (F) werealso evaluated in both mice groups. n = 4 mice per group. (*) Indicates p < 0.05.

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