Table 1 Serum sodium (Na), potassium (K), chloride (Cl), lactate dehydrogenase (LDH), creatine phosphokinase (CPK), and C-reactive protein (CRP) concentrations 2 hours, 1 and 3 weeks after cast removal, and 2 hours after ischemic reperfusion (IR).

From: Therapeutic effects of diclofenac, pregabalin, and duloxetine on disuse-induced chronic musculoskeletal pain in rats

 

Untreated

2-hour

1-week

3-week

IR-2-hour

LDH (U/L)

69.83 ± 6.42

69.83 ± 6.42 n.s.

66.20 ± 5.65 n.s.

74.20 ± 6.45 n.s.

1375.60 ± 564.9*,#

CPK (U/L)

90.33 ± 7.39

152.60 ± 8.67 n.s

104.00 ± 6.15 n.s.

100.4 ± 8.21 n.s

3363.80 ± 992.14***,##

Na (mEq/L)

141.17 ± 0.40

143.60 ± 1.29 n.s

140.20 ± 0.37 n.s.

140.80 ± 0.86 n.s.

141.60 ± 1.08n.s.

Cl (mEq/L)

99.00 ± 0.63

102.20 ± 0.86 n.s.

100.20 ± 0.37n.s.

99.20 ± 0.58 n.s.

100.60 ± 0.68 n.s.

K (mEq/L)

4.983 ± 0.183

4.760 ± 0.103n.s.

4.980 ± 0.248 n.s.

5.720 ± 0.302 n.s.

4.940 ± 0.201 n.s.

CRP (mg/dL)

<0.05

<0.05 n.s.

<0.05 n.s.

<0.05 n.s.

<0.05 n.s.

  1. Values are presented as mean ± standard error of the mean (n = 5). n.s.: no significant, *P < 0.05 and ***P < 0.001 difference relative to the untreated group (Scheffe’s multiple comparison test). #P < 0.05 and ##P < 0.01 relative to the group of 2 hours after cast removal.
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