Figure 2 | Scientific Reports

Figure 2

From: c-Jun N-terminal kinase 1 defective CD4+CD25+FoxP3+ cells prolong islet allograft survival in diabetic mice

Figure 2

Lack of JNK1 expression enhances survival of Tregs in recipient mice. Pancreatic islets and Tregs from WT or JNK1−/− mice (CD45.2) were transferred to diabetic mice (CD45.1) as in Fig. 1a. Three, thirty and one hundred twenty days after transplantation, the percentages of donor-derived (CD45.2) cells in recipient mouse liver were determined by flow cytometry. (a) Schematic representation of the experiment. (b) Absolute number of cells. (c) A representative flow cytometry figure. Data presented are representative of five independent experiments. Five mice per group were used. Mean values, p values and SEs are shown.

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