Table 2 Differentially expressed small ncRNAs in PE vs. control sample.

From: Early Detection of Preeclampsia Using Circulating Small non-coding RNA

Transcript

Transcript ID

Transcript Biotype

Mean Counts

Fold Change

P-Value

Adjusted p-Value

mitochondrially encoded tRNA proline

ENST00000387461

Mitochondrial tRNA

490

4.25

1.65 × 10−16

1.57 × 10−14

mitochondrially encoded tRNA lysine

ENST00000387421

Mitochondrial tRNA

433

2.27

3.43 × 10−6

1.63 × 10−4

microRNA 182

ENST00000385255

miRNA

1,325

0.54

5.45 × 10−6

1.73 × 10−4

microRNA 10b

ENST00000385011

miRNA

7115

0.50

8.96 × 10−6

2.13 × 10−4

mucin 2, oligomeric mucus/gel−forming

ENST00000361558

processed transcript

901

2.34

1.68 × 10−5

3.19 × 10−4

microRNA 25

ENST00000384816

miRNA

5,585

0.61

5.38 × 10−5

6.39 × 10−4

RP11–259O2.3-001

ENST00000514519

lincRNA

409

2.97

4.92 × 10−5

6.39 × 10−4

microRNA 4433b

ENST00000581329

miRNA

473

1.71

4.98 × 10−5

6.39 × 10−4

mitochondrially encoded tRNA histidine

ENST00000387441

Mitochondrial tRNA

247

1.95

9.21 × 10−5

9.72 × 10−4

HELLP associated long non-coding RNA

ENST00000626826

macro lncRNA

729

2.02

1.08 × 10−4

1.03 × 10−3

microRNA 99b

ENST00000384819

miRNA

344

0.65

1.57 × 10−4

1.31 × 10−3

microRNA 143

ENST00000385300

miRNA

1,632

0.62

1.66 × 10−4

1.31 × 10−3

mitochondrially encoded tRNA valine

ENST00000387342

Mitochondrial tRNA

664

1.99

2.11 × 10−4

1.54 × 10−3

microRNA 151a

ENST00000521276

miRNA

10,021

0.75

5.68 × 10−4

3.85 × 10−3

microRNA 191

ENST00000384873

miRNA

31,187

0.75

6.26 × 10−4

3.97 × 10−3

RNA, 5.8 S ribosomal pseudogene 4

ENST00000365096

rRNA

1,652

1.68

1.65 × 10−3

9.21 × 10−3

mitochondrially encoded tRNA serine 2 (AGU/C)

ENST00000387449

Mitochondrial tRNA

1,250

1.72

1.61 × 10−3

9.21 × 10−3

microRNA 146b

ENST00000365699

miRNA

1,323

0.75

2.67 × 10−3

1.41 × 10−2

microRNA 221

ENST00000385135

miRNA

587

1.44

3.97 × 10−3

1.98 × 10−2

mitochondrially encoded tRNA tyrosine

ENST00000387409

Mitochondrial tRNA

173

1.53

4.41 × 10−3

2.09 × 10−2

mitochondrially encoded 16 S RNA

ENST00000387347

Mitochondrial tRNA

6,218

1.63

4.82 × 10−3

2.18 × 10−2

microRNA let-7g

ENST00000362280

miRNA

1,073

1.27

9.85 × 10−3

4.26 × 10−2

long intergenic non-protein coding RNA 324

ENST00000315707

lincRNA

1,087

1.50

1.03 × 10−2

4.27 × 10−2

AC113133.1-201 (microRNA-486)

ENST00000612171

miRNA

17,569

0.70

1.11 × 10−2

4.38 × 10−2

AC020956.3-001

ENST00000614316

lincRNA

902

1.71

1.18 × 10−2

4.47 × 10−2

  1. Each of the most highly abundant transcripts in the women’s plasma was tested for differential expression in 35 PE vs. 40 control samples, and 25 transcripts were found to be differentially expressed (FDR adjusted p-value < 0.05).
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