Figure 3
Lung Structure of MGP Genotypes at 25 days of Age. MGP heterozygous males and females were mated. At the start of pregnancy dams were fed either a control or a high-fat diet. These diets were continued throughout pregnancy and after birth. Wild type (WT) and MGP knockout (KO) offspring were analysed at 25 days of age. Graphs shows (a). Total lung tissue volume as determined by CT. (b) Percentage of total lung tissue volume with thickness of less than 200 µm. (c) Percentage of total lung tissue volume with thickness greater than 400 µm. (d) Total lung air volume. (e) Percentage of total lung airway volume with thickness of less than 200 µm. For all graphs, results are shown by sex, n = 6–14 per group. Bar charts show mean plus 95% confidence limits.
