Table 5 Linear regression analysis between gene expression levels and body parameters.

From: The influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice

Body Parameter	Aortic Sclerostin				Aortic Bmp-1				Aortic ER alpha				Aortic Angiotensinogen
Body Parameter	β	r²	F	p	β	r²	F	p	β	r²	F	p	β	r²	F	p
% Bone	−0.4	0.18	12.5	0.001	−0.4	0.19	12.9	0.001	−0.5	0.27	20.6	<0.001	0.7	0.49	50.1	<0.001
% Fat	0.4	0.17	12.2	0.001	0.4	0.17	11.2	0.001	0.5	0.26	19.5	<0.001	−0.6	0.34	26.9	<0.001
% Soft tissue	−0.4	0.13	8.8	0.004	−0.4	0.13	8.2	0.006	−0.4	0.20	13.7	<0.001	0.5	0.24	17.1	<0.001
% Brown Adipose Tissue	−0.5	0.23	16.1	<0.001	−0.5	0.27	20.0	<0.001	−0.4	0.18	11.0	0.002	0.4	0.17	10.1	0.003
% Calcified soft tissue	−0.7	0.42	42.5	<0.001	−0.5	0.24	17.6	<0.001	−0.6	0.41	37.8	<0.001	0.7	0.55	64.7	<0.001
% Lung tissue	0.2	0.04	2.3	NS	0.0	0.00	0.0	NS	−0.1	0.01	0.6	NS	−0.1	0.01	0.8	NS
% Lung airways	0.2	0.00	0.0	NS	−0.2	0.04	1.5	NS	−0.1	0.00	0.1	NS	−0.1	0.02	0.6	NS
Length	0.5	0.25	19.2	<0.001	0.5	0.21	15.4	<0.001	0.5	0.27	20.4	<0.001	−0.6	0.35	27.9	<0.001
Mass	0.5	0.30	24.4	<0.001	0.4	0.15	9.8	0.003	0.4	0.17	11.0	0.002	−0.6	0.34	26.9	<0.001
Body Parameter	Aortic *Ggcx*				Aortic *Vkor*				Aortic *Mgp*				Femoral Gas6
Body Parameter	β	r²	F	p	β	r²	F	p	β	r²	F	p	β	r²	F	p
% Bone	−1.3	0.33	28.2	<0.001	−1.1	0.24	17.5	<0.001	−0.6	0.24	18.0	<0.001	0.7	0.27	20.3	<0.001
% Fat	4.2	0.12	8.0	0.006	4.8	0.16	10.7	0.002	2.4	0.11	7.1	0.01	−2.4	0.11	6.6	0.01
% Soft tissue	−2.8	0.07	4.0	0.05	−3.6	0.12	7.4	0.009	−1.6	0.06	3.9	0.05	1.7	0.07	3.9	0.05
% Brown Adipose Tissue	−0.4	0.23	15.8	<0.001	−0.3	0.11	6.2	0.02	−0.3	0.25	17.8	<0.001	0.1	0.03	1.9	NS
% Calcified soft tissue	−0.2	0.40	37.4	<0.001	−0.1	0.26	20.1	<0.001	−0.1	0.55	70.4	<0.001	0.06	0.15	9.6	0.003
% Lung tissue	−0.4	0.04	2.5	NS	−0.08	0.00	0.1	NS	−0.05	0.00	0.1	NS	0.2	0.02	1.2	NS
% Lung airways	−0.03	0.02	0.7	NS	−0.04	0.03	1.4	NS	−0.00	0.00	0.01	NS	0.02	0.01	0.5	NS
Length	8.1	0.33	28.3	<0.001	7.5	0.30	23.4	<0.001	3.8	0.21	14.7	<0.001	−2.4	0.08	4.5	0.04
Mass	5.2	0.31	25.6	<0.001	4.7	0.28	21.3	<0.001	2.8	0.26	20.1	<0.001	−1.3	0.05	2.8	NS
Body Parameter	Femoral Ggcx				Femoral *Vkor*				Femoral Mgp				Femoral *Periostin*
Body Parameter	β	r²	F	p	β	r²	F	p	β	r²	F	p	β	r²	F	p
% Bone	−0.9	0.19	12.4	0.001	−0.8	0.17	11.6	0.001	−0.7	0.20	13.4	0.001	−1.1	0.38	30.7	<0.001
% Fat	3.0	0.07	4.2	0.05	2.1	0.04	2.4	NS	1.4	0.03	1.9	NS	3.8	0.14	8.2	0.006
% Soft tissue	−2.0	0.04	2.3	NS	−1.2	0.02	1.0	NS	−0.6	0.01	0.4	NS	−2.5	0.08	4.1	0.05
% Brown Adipose Tissue	−0.4	0.19	11.7	0.001	−0.2	0.08	4.3	0.04	−0.3	0.21	14.1	<0.001	−0.4	0.23	14.4	<0.001
% Calcified soft tissue	−0.1	0.24	16.7	<0.001	−0.1	0.25	19.1	<0.001	−0.1	0.47	49.6	<0.001	−0.2	0.52	53.6	<0.001
% Lung tissue	−0.1	0.00	0.2	NS	−0.06	0.00	0.07	NS	−0.1	0.01	0.4	NS	−0.3	0.03	1.4	NS
% Lung airways	0.03	0.02	0.6	NS	−0.01	0.00	0.04	NS	−0.03	0.13	6.1	0.02	−0.02	0.05	1.8	NS
Length	5.4	0.17	11.1	0.002	3.9	0.10	6.1	0.02	2.7	0.08	5.1	0.03	7.2	0.36	27.7	<0.001
Mass	3.2	0.14	8.9	0.004	3.1	0.15	9.9	0.003	2.3	0.15	9.4	0.003	5.4	0.45	40.2	<0.001

% values are as percentage of total body volume. NS: Not statistically significant.

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Table 5 Linear regression analysis between gene expression levels and body parameters.

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