Table 6 Linear regression analysis between gene expression levels and body parameters.

From: The influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice

Multivariant analysis

Body Parameter

r

r2

F

p

 

% Bone

0.86

0.75

23.6

<0.001

 

% Fat

0.59

0.34

4.2

0.004

Femoral VKDP Genes:

% Soft tissue

0.48

0.23

2.5

0.05

Gas6

% Brown Adipose Tissue

0.64

0.41

5.2

0.001

Periostin

% Calcified soft tissue

0.89

0.79

29.2

<0.001

Mgp

% Lung Tissue

0.40

0.16

1.5

NS

Ggcx

% Lung airways

0.63

0.40

3.6

0.02

Vkor

Length

0.67

0.45

6.6

<0.001

Mass

0.68

0.46

6.7

<0.001

% Bone

0.61

0.37

10.5

<0.001

Aortic VKDP Genes:

% Fat

0.44

0.19

4.3

0.009

Mgp

% Soft tissue

0.36

0.13

2.7

0.05

Ggcx

% Brown Adipose Tissue

0.53

0.28

6.7

0.001

Vkor

% Calcified soft tissue

0.78

0.60

27.1

<0.001

% Lung Tissue

0.26

0.07

1.3

NS

% Lung airways

0.20

0.04

0.5

NS

Length

0.62

0.38

11.0

<0.001

Mass

0.62

0.39

11.3

<0.001

% Bone

0.76

0.57

16.7

<0.001

Aortic Non-VKDP Genes:

% Fat

0.73

0.53

14.3

<0.001

Sclerostin

% Soft tissue

0.65

0.43

9.4

<0.001

Bmp-1

% Brown Adipose Tissue

0.61

0.37

6.8

<0.001

ER alpha

% Calcified soft tissue

0.85

0.72

32.1

<0.001

Angiotensinogen

% Lung Tissue

0.27

0.07

0.9

NS

% Lung airways

0.33

0.11

1.1

NS

Length

0.71

0.51

13.0

<0.001

Mass

0.69

0.47

11.1

<0.001

Femoral VKDP and Aortic VKDP Genes

% Bone

0.88

0.78

15.5

<0.001

combined

% Fat

0.67

0.45

3.5

0.004

 

% Soft tissue

0.58

0.34

2.3

0.05

% Brown Adipose Tissue

0.72

0.52

4.5

0.001

% Calcified soft tissue

0.92

0.85

25.0

<0.001

% Lung Tissue

0.50

0.25

1.4

NS

% Lung airways

0.64

0.41

2.0

0.09

Length

0.78

0.60

6.6

<0.001

Mass

0.77

0.59

6.3

<0.001

Femoral and all Aortic Genes

% Bone

0.93

0.87

15.9

<0.001

combined

% Fat

0.82

0.67

4.8

<0.001

 

% Soft tissue

0.77

0.59

3.4

0.004

% Brown Adipose Tissue

0.82

0.67

4.4

0.001

% Calcified soft tissue

0.95

0.90

21.1

<0.001

% Lung Tissue

0.66

0.43

1.8

NS

% Lung airways

0.84

0.70

3.1

0.02

Length

0.82

0.68

4.9

<0.001

Mass

0.83

0.68

5.0

<0.001

  1. % values are as percentage of total body volume. NS: Not statistically significant.
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