Figure 4

Blood plasma cytokine panel time-course analysis following single-dose RFT. At 24, 48, or 120 hrs after a single RFT blood plasma was analyzed for 25 cytokines. (a) Cytokine plasma concentration fold-change of RF-treated mice at 24, 48, or 120 hours post-RFT compared to control mice. Fold changes for each analyte were calculated by taking the ratio of average plasma concentrations of RFT-mice and control mice for each independent time-point (i.e. [G-CSF]24 hr RF/[G-CSF]24 hr Control) (n = 5/group). (b) Plasma concentration in pg/mL of IL-6 (top) and MIP2 (bottom) comparing control and RF-treated mice 24hrs post-RFT (n = 5/group). Error bars represent SEM. (*p < 0.05).