Table 1 One possible combination of parameters with which the tLIR model of11 fits empirical data well. We are restricting r to be in the range [10−10, 10−6] as was done by11.
Cancer | k | r | R 2 | Stem cell | Division rate | Generation1 | Risk |
|---|---|---|---|---|---|---|---|
AML | 4.8 | 1.000e − 06 | 1.00 | 1.35e + 08 | 12.000 | 1047.01 | 4.651e − 03 |
BCC | 4.5 | 1.000e − 06 | 0.98 | 5.82e + 09 | 7.600 | 678.44 | 2.181e − 04 |
CLL | 4.9 | 1.000e − 06 | 0.99 | 1.35e + 08 | 12.000 | 1047.01 | 6.925e − 03 |
COAD | 5.5 | 5.012e − 07 | 1.00 | 2.00e + 08 | 73.000 | 6232.58 | 5.677e − 02 |
DUAD | 5.3 | 1.000e − 06 | 1.00 | 4.00e + 06 | 24.000 | 2061.93 | 3.714e − 04 |
ESCA | 4.5 | 5.012e − 07 | 0.99 | 8.64e + 05 | 17.400 | 1498.72 | 3.106e − 03 |
GBNPAD | 3.5 | 1.000e − 06 | 0.85 | 1.60e + 06 | 0.584 | 70.25 | 1.896e − 03 |
GBM* | 1.35e + 08 | 0.000 | 27.01 | 3.825e − 03 | |||
HNSC | 3.8 | 1.995e − 07 | 0.99 | 1.85e + 07 | 21.500 | 1851.64 | 1.730e − 02 |
LHCA | 3.6 | 1.000e − 06 | 0.94 | 3.01e + 09 | 0.912 | 109.05 | 7.079e − 03 |
LUAD | 2.8 | 7.943e − 08 | 0.83 | 1.22e + 09 | 0.070 | 36.13 | 2.304e − 02 |
MBM* | 1.36e + 08 | 0.000 | 27.02 | 1.414e − 04 | |||
SKCM | 3.8 | 1.000e − 06 | 1.00 | 3.80e + 09 | 2.480 | 242.62 | 3.038e − 02 |
OSARC | 1.0 | 1.585e − 08 | 0.96 | 4.18e + 06 | 0.067 | 27.69 | 2.696e − 04 |
OSARCA | 1.0 | 6.310e − 07 | 0.96 | 6.50e + 05 | 0.067 | 25.01 | 2.527e − 05 |
OSARCH | 3.0 | 1.000e − 06 | 0.99 | 8.60e + 05 | 0.067 | 25.41 | 1.660e − 05 |
OSARCL | 1.0 | 3.981e − 07 | 0.96 | 1.59e + 06 | 0.067 | 26.30 | 1.312e − 04 |
OSARCP | 3.1 | 1.000e − 06 | 0.91 | 4.50e + 05 | 0.067 | 24.47 | 3.229e − 05 |
OVGC* | 1.10e + 07 | 0.000 | 23.39 | 7.638e − 05 | |||
PDAD | 3.8 | 1.000e − 06 | 0.92 | 4.18e + 09 | 1.000 | 116.96 | 1.016e − 02 |
PECA | 3.6 | 1.000e − 06 | 0.99 | 7.40e + 07 | 1.000 | 111.14 | 1.498e − 04 |
SIAD | 5.0 | 5.012e − 07 | 1.00 | 1.00e + 08 | 36.000 | 3086.58 | 8.013e − 04 |
TGCC | 1.9 | 7.943e − 07 | 0.96 | 7.20e + 06 | 5.800 | 515.78 | 2.244e − 03 |
TPFC | 3.1 | 1.000e − 06 | 0.98 | 6.50e + 07 | 0.087 | 33.35 | 6.922e − 03 |
TMCA | 3.1 | 7.943e − 07 | 0.93 | 6.50e + 06 | 0.087 | 30.03 | 8.707e − 05 |