Figure 2 | Scientific Reports

Figure 2

From: Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism

Figure 2

Co-localization of red GLP-1R, green GLP-1 and blue Rab11 in islets of non-diabetic and diabetic rats. CLM images of a (a) 25-week-old non-diabetic Wistar rat (BW 489 g, FBS 119 mg/dl) and (b) 25-week-old diabetic GK rat (BW 419 g, FBS 230 mg/dl) taken at 20× magnification. The yellow arrow in Fig. 2a indicates a small red dot in non-alpha cells. The red rectangular area in Fig. 2b is split and shown again in Supple. Figure 4. The yellow rectangular area in Fig. 2b is shown again in Fig. 4e and f.

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