Figure 7 | Scientific Reports

Figure 7

From: Global Gene Expression Analysis in an in vitro Fibroblast Model of Idiopathic Pulmonary Fibrosis Reveals Potential Role for CXCL14/CXCR4

Figure 7The alternative text for this image may have been generated using AI.

Histological localization of CXCR4 to ACTA2+ cells and EpCAM+ cells in IPF. Representative images of three IPF tissue sections are stained for the presence of CXCR4 (C,G,K,O,S,W). Fibrotic foci stain positive for ACTA2 throughout but only show co-localization (denoted in yellow) with CXCR4 near the peripheral edges (L). Areas of dense fibrosis stain show co-localization of CXCR4 and ACTA2 (D,H) and the minimal presence of non-CXCR4 co-localized EpCAM (N,V,R).

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