Table 1 Number of dead and transponder-implanted animals, time of death and last recorded core and surface temperatures before death following lipopolysaccharide (LPS) injection per genotype. No transponder-implanted Cd11b animals died, thus their near-death core temperature was not assessed. N/A: not applicable.
C57BL/6 | Mertk | Cd11b | Mfge8 | |
|---|---|---|---|---|
Number of dead animals | 3 (1 euthanized, 2 found dead) | 17 (4 euthanized, 13 found dead) | 2 (2 euthanized) | 8 (5 euthanized, 3 found dead) |
Number of dead animals with transponder implant | 3 | 4 | 0 | 8 |
Core temperature before death (°C) | max = 28.7 min = 24.9 average = 26.6 (1.6) | max = 29.3 min = 22.3 average = 24.2 (3.0) | N/A | max = 31.6 min = 20.5 average = 24.5 (3.7) |
Surface temperature before death (°C) | max = 25.9 min = 24.4 average = 25.1 (0.5) | max = 28.9 min = 20.2 average = 23.3 (1.9) | max = 21.3 min = 19.0 average = 20.3 (0.9) | max = 27.1 min = 21.2 average = 23.4 (1.9) |
Time of death (hours after the first injection) | max = 104.5 min = 36.0 average = 66.8 (30.1) | max = 192.0 min = 31.5 average = 67.6 (39.9) | max = 72.0 min = 54.0 average = 63.0 (9.9) | max = 97.5 min = 24.0 average = 42.6 (22.8) |
