Figure 8

Metformin (MH) plasma concentrations after s.c. administration of 100 mg of metformin solution (MH Sol) or metformin-loaded gel (MH Gel) at the same concentration for 15 days. Values are reported as means ± S.E.M. of the measurement of plasma concentration from 7 mice (t-test: *p < 0.05 vs. MH Sol).