Figure 4

Pathway analysis of metabolites that are increased or decreased in rats with heart failure, and the effect of treatment with QL or benazepril. AA: arachidonic acid; Be: benazepril; COX: cyclooxygenase; CYP450: cytochrome P450; DHA: docosahexaenoic acid; EPA: eicosapentaenoic acid; FFA: free fatty acid; HF: heart failure; LA: linoleic acid; LOX: lipoxygenase; RNS: reactive nitrogen species; TCA: tricarboxylic acid.