Figure 8 | Scientific Reports

Figure 8

From: RETRACTED ARTICLE: Electrochemical Sensor for Detection of miRs Based on the Differential Effect of Competitive Structures in The p19 Function

Figure 8

Schematic drawing of Sequential Detection of 124a-221-21 miRs by the liposomal-p19 sensor in one electrod. (A) A self-assembled of M-linear and Stem probes mix on the same DOPE/DOTAP/AuNP electrode. (B) Incubation of sensor with miR124a caused an increase in resistance measured by EIS. (C) p19 protein caused decreased in resistance and thus improved the detection range. (D) Hybridization of mir 221 and Stem probe increase in resistance. (E) Adding p19 protein decreased in resistance, again. (F) Adding free T-linear probe/21 miR caused a shift back (increase) in resistance.

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