Figure 4
From: Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors

Methylation analsis of patient 1. (A) Average beta values of primary (left) and metastasis (right) in comparison to normal tissue of patient 1. 0 = fully unmethylated, 1 = fully methylated. (B) Comparison of genes harbouring promotor associated CpG sites with marked (>0.3 delta beta value) hypo- and hypermethylation in patient 1 and the COSMIC cancer gene census.