Table 1 Patient characteristics. Clinical characteristics of the study cohort. P: primary, M: metastasis, hep: hepatic, os: osseous, M.r.s.: Musculus rectus superior, SST: somatostatin analogue, TACE: transarterial chemoembolization, PRRT: Peptide Receptor Radionuclide Therapy, Tem: temozolomide, Cap: capecitabine, Ox: oxaliplatin, Bev: Bevacizumab, SD: stable disease.

From: Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors

PAT ID

SEX

AGE

G

KI67 P

KI67 M

T

N

M

L

V

PN

R

THERAPY

STATUS

1

F

60

G1

<2%

<2%

3

1

hep.

1

0

1

0

SST -> SD

alive

2

M

57

G2

10%

10%

3

0

hep., os.

1

1

1

1

SST/TACE/PRRT -> SD

alive

3

F

67

G2

10–15%

10–15%

4

1

hep.

1

1

1

0

SST ->SST/TACE ->PRRT -> TACE/SST

alive

4

M

68

G2

4–5%

<2%

3

0

hep.

1

1

1

0

SST, Everolimus, Tem/Cap, Cap/Ox/Bev

deceased

5

M

52

G1

<2%

5%

2

1

hep., os., M.r.s.

1

1

0

0

SST

deceased