Table 1 Summary of next-generation sequencing results at the onset of bloodstream infection.

From: Comprehensive detection of pathogens in immunocompromised children with bloodstream infections by next-generation sequencing

Patient ID

Sequence depth (reads)

Bacteria isolated from blood culture

Reads (per million reads)*

Dominant bacteria by NGS (species)**

Reads (per million reads) *

B1

9,895,348

Escherichia coli

2,575

Escherichia coli

2,575

B2

9,753,018

Capnocytophaga sputigena

0.3

Delftia sp. strain Cs1-4

179

B3

21,983,948

Streptococcus oralis/mitis

444/6

Streptococcus mitis

444

B4

32,895,328

Stenotrophomonas maltophilia

267

Stenotrophomonas maltophilia

267

B5

10,166,160

Staphylococcus aureus

7

Streptococcus pyogenes

223

B6

22,769,288

Acinetobacter ursingii

1

Moraxella osloensis

4

B7

16,968,966

Stenotrophomonas maltophilia

1,415

Stenotrophomonas maltophilia

1,415

B8

4,793,796

Streptococcus oralis/mitis

7/3

Pseudomonas stutzeri

172

B9

24,026,704

Bacillus cereus

54

Bacillus anthracis

80

B10

20,027,612

Sphingomonas paucimobilis

25

Sphingobium sp. strain TKS

34

B11

9,305,716

Staphylococcus lugdunensis

36

Staphylococcus epidermidis

25

B12

17,397,938

Staphylococcus epidermidis

27,719

Staphylococcus epidermidis

27,719

  1. *The number of the reads derived from isolated bacteria in blood culture per million reads of sequencing.
  2. **The reads classified as Propionibacterium acnes were discarded.
  3. These bacteria were classified at the genus level.