Table 2 Action potential characterization for small DRG neurons (20–25 µm) from AAV-Cre mediated NaV1.6 null mice and control wild-type mice.
From: Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain
NaV1.6flox/flox | Resting membrane potential (mV) | Input resistance (MΩ) | Action potential amplitude (mV) | Current threshold (pA) |
|---|---|---|---|---|
AAV-GFP (n = 7) | −55.4 ± 2.3 | 140 ± 27 | 111 ± 5.2 | 267 ± 104 |
AAV-CRE (n = 7) | −50.5 ± 2.7 | 539 ± 199 | 110 ± 4.8 | 222 ± 117 |
p-value | 0.192 | 0.0707 | 0.850 | 0.779 |
