Figure 3
From: Significance of risk polymorphisms for depression depends on stress exposure

Illustration of dependency relationships included in GLM models investigating the role of genetic and environmental factors with respect to depression phenotypes. Relationships ‘a’ recent life events (RLE) and ‘b’ represent the main effect of genetic factors, respectively, on depression phenotypes. Relationship ‘c’ represents the interaction between genetic factors and RLE. Model 1: effect of ‘a’. Model 2: effect of ‘a + b’. Model 3: effect of ‘a + b + c’.