Table 1 Population description.
From: Significance of risk polymorphisms for depression depends on stress exposure
Demographics | ALL | BUD | MAN | |
|---|---|---|---|---|
gender | male (%) | 509 (30.3%) | 226 (33.7%) | 283 (28%) |
female (%) | 1173 (69.7%) | 445 (66.3%) | 728 (72%) | |
age | mean (SD) | 33.23 (10.53) | 31.78 (10.54) | 34.2 (10.42) |
lifetime depression (DEP) | no (%) | 958 (57%) | 524 (78.1%) | 434 (42.9%) |
yes (%) | 724 (43%) | 147 (21.9%) | 577 (57.1%) | |
recent negative life events (RLE) | ||||
low (%) | 1134 (67.4%) | 479 (71.8%) | 651 (64.4%) | |
moderate (%) | 311 (18.5%) | 120 (18%) | 191 (18.9%) | |
high (%) | 237 (14.1%) | 68 (10.2%) | 169 (16.7%) | |
current depression score (BSI-DEP) | ||||
low (%) | 1133 (67.4%) | 543 (80.9%) | 590 (58.4%) | |
moderate (%) | 290 (17.2%) | 92 (13.7%) | 198 (19.6%) | |
severe (%) | 259 (15.4%) | 36 (5.4%) | 223 (22.1%) | |
current anxiety score (BSI-ANX) | ||||
low (%) | 1096 (65.2%) | 503 (75%) | 593 (58.7%) | |
moderate (%) | 339 (20.2%) | 122 (18.2%) | 217 (21.5%) | |
severe (%) | 247 (14.7%) | 46 (6.9%) | 201 (19.9%) | |
Genetic variables | ||||
5-HTTLPR | ss (%) | 307 (18.3%) | 114 (17%) | 193 (19.1%) |
sl (%) | 819 (48.7%) | 328 (48.9%) | 491 (48.6%) | |
ll (%) | 556 (33.1%) | 229 (34.1%) | 327 (32.3%) | |
rs6265 (BDNF) | GG (%) | 1128 (67.1%) | 442 (65.9%) | 686 (67.9%) |
AG (%) | 484 (28.8%) | 202 (30.1%) | 282 (27.9%) | |
AA (%) | 70 (4.2%) | 27 (4%) | 43 (4.3%) | |
rs6295 (HTR1A) | GG (%) | 425 (25.3%) | 174 (25.9%) | 251 (24.8%) |
GC (%) | 845 (50.2%) | 366 (54.5%) | 479 (47.4%) | |
CC (%) | 412 (24.6%) | 131 (19.5%) | 281 (27.8%) | |
rs6311 (HTR2A) | CC (%) | 569 (33.8%) | 224 (33.4%) | 345 (34.1%) |
CT (%) | 832 (49.5%) | 314 (46.8%) | 518 (51.2%) | |
TT (%) | 281 (16.7%) | 133 (19.8%) | 148 (14.6%) | |
rs7766029 (CB1) | CC (%) | 443 (26.3%) | 164 (24.4%) | 207 (20.5%) |
CT (%) | 868 (51.6%) | 352 (52.5%) | 516 (51%) | |
TT (%) | 371 (22.1%) | 155 (23.1%) | 288 (28.5%) | |
rs7958311 (P2RX7) | GG (%) | 983 (58.4%) | 422 (62.9%) | 561 (55.5%) |
AG (%) | 610 (36.3%) | 212 (31.6%) | 398 (39.4%) | |
AA (%) | 89 (6.3%) | 37 (5.5%) | 52 (5.1%) | |
rs8836 (GALR2) | CC (%) | 580 (34.5%) | 216 (32.2%) | 364 (36%) |
CG (%) | 820 (48.7%) | 338 (50.4%) | 482 (47.7%) | |
GG (%) | 282 (16.8%) | 117 (17.4%) | 165 (16.3%) | |
