Table 3 Association status of significant SNPs with obesity and other related parameters in GIANT consortium data.
From: Common variants of ARID1A and KAT2B are associated with obesity in Indian adolescents
Gene | SNP | Chr | Position_hg19 | RA/OA | Sample_size | Effect | Standard error | P | Trait | Sample group |
|---|---|---|---|---|---|---|---|---|---|---|
ARID1A | rs6598860 | 1 | 27041714 | A/G | 253288 | 0.01 | 0.005 | 0.04 | BMI | Mixed ancestry individuals |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 75552 | 0.02 | 0.0056 | 5.03 × 10–3 | WHR | Women of mixed ancestry adjusted for physical activity |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 71104 | 0.02 | 0.0058 | 0.01 | WHR | European women adjusted for physical activity |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 58558 | 0.02 | 0.0063 | 0.02 | WHR adjusted BMI | Physically active woman of mixed ancestry |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 71426 | 0.01 | 0.0057 | 0.03 | BMI | Physically active man of mixed ancestry |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 55519 | 0.01 | 0.0065 | 0.05 | WHR adjusted for BMI | Physically active European women |
ARID1A | rs4589135 | 1 | 27041714 | C/T | 103871 | 0.01 | 0.0049 | 0.05 | WC adjusted for BMI | Physically active European |
KAT2B | rs3804562 | 3 | 20181028 | T/C | 52137 | 0.02 | 0.0091 | 0.03 | WHR adjusted for BMI and physical activity | A ancestry men |
KAT2B | rs3804562 | 3 | 20181028 | T/C | 126190 | 0.01 | 0.0063 | 0.05 | WHR adjusted for BMI and physical activity | Mixed ancestry individuals |
