Figure 5 | Scientific Reports

Figure 5

From: Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity

Figure 5

MTBC phylogeny comprising the seven major lineages. The figure represents the number of TFs missing or potentially affected in their regulatory functions in one or more clinical strains from the Comas et al.15 MTBC reference dataset (n = 219 strains). Mutations affecting a TF are mapped to the corresponding internal/external node of the Comas et al. phylogeny and highlighted in colour. Green colour indicates total or partial deletions of a TF, yellow indicates stop-codon gain or loss, and blue indicates a SNP in the regulatory region of a TF. The maximum-likelihood phylogeny was obtained from a genome-wide SNP alignment as described in Comas et al.15.

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