Figure 7 | Scientific Reports

Figure 7

From: Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity

Figure 7

ChIP-Seq coverage comparison and regulatory influences between the phoP knock-out, wild-type and phoP overexpressed strains. (A) Circle representation of the H37Rv reference genome. From outside to inside: ChIP-Seq coverage of phoP knock-out mutant, wild-type and TFOE. The inner links represent the regulatory influence of phoP derived from TFOE (blue), mutant strain (purple) and their overlap (black). (B) Detail of two selected genes with regulatory influences derived from TFOE that do not match the evidence from WT and the mutant strain.

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