Figure 8

Schematic representation of the role of GNMT in AAI metabolism. The proposed metabolic pathways of AAI regulated by GNMT in liver of 5 mg/kg/day AAI-treated female WT mice (a) and GNMT Tg mice (b); and in 2 mg/kg/day AAI-treated male WT mice (c) and GNMT Tg mice (d).