Table 1 Baseline characteristics of end-stage kidney disease patients who have experienced different causes of peritoneal dialysis technique failure (n = 4663).

From: Association between causes of peritoneal dialysis technique failure and all-cause mortality

 

Infection (n = 2415)

Inadequate Dialysis (n = 883)

Mechanical (n = 836)

Social (n = 529)

Total (n = 4663)

p-value

Demographics

  Male (n, %)

1219 (51)

574 (65)

436 (52)

313 (59)

2542 (55)

<0.001

  Age starting PD (year, mean ± SD)

59.0 ± 13.6

54.9 ± 14.6

59.3 ± 13.2

59.2 ± 16.1

58.3 ± 14.1

<0.001

  Age of PD failure (year, mean ± SD)

60.8 ± 13.7

56.9 ± 14.7

60.5 ± 13.2

60.8 ± 16.3

60.0 ± 14.2

<0.001

  BMI (mean ± SD)

26.8 ± 5.4

27.5 ± 5.4

27.0 ± 5.3

26.9 ± 5.2

27.0 ± 5.4

0.005

  Ethnicity (n, %)

     

0.003

   Caucasian

1629 (68)

639 (72)

608 (73)

481 (72)

3257 (70)

 

   Indigenous^

400 (17)

106 (12)

103 (12)

79 (15)

688 (15)

 

   Others

386 (16)

138 (16)

125 (15)

69 (13)

718 (15)

 

Comorbidities

  Lung disease (n, %)

223 (9)

65 (7)

96 (12)

59 (11)

443 (10)

0.015

  Coronary artery disease (n, %)

680 (28)

198 (22)

232 (28)

131 (25)

1241 (27)

0.006

  Peripheral vascular disease (n, %)

373 (15)

134 (15)

124 (15)

99 (19)

730 (16)

0.22

  Cerebrovascular disease (n, %)

255 (11)

62 (7)

96 (12)

64 (12)

477 (10)

0.003

  Diabetes (n, %)

986 (41)

356 (40)

288 (34)

224 (42)

1854 (40)

0.006

Smoker (n, %)

     

0.13

  Non-smoker

1109 (46)

444 (50)

384 (46)

230 (44)

2167 (47)

 

  Current smoker

338 (14)

125 (14)

113 (14)

87 (17)

663 (14)

 

  Ex-smoker

959 (40)

312 (35)

337 (40)

210 (40)

1818 (39)

 

Cause of ESKD (n,%)

     

<0.001

  Glomerulonephritis

560 (23)

248 (28)

204 (24)

113 (21)

1125 (24)

 

  Diabetes

821 (34)

288 (33)

213 (26)

175 (33)

1497 (32)

 

  Cystic

152 (6)

62 (7)

104 (12)

37 (7)

355 (8)

 

  Vascular

280 (12)

91 (10)

115 (14)

67 (13)

553 (12)

 

  Analgesic nephropathy

124 (5)

34 (4)

29 (4)

22 (4)

209 (5)

 

  Others

478 (20)

160 (18)

171 (21)

115 (22)

924 (20)

 

Peritoneal dialysis characteristics

  Duration of PD (years, median ± IQR)

1.8 ± 2.2

2.0 ± 2.2

1.2 ± 1.7

1.6 ± 2.0

1.7 ± 2.1

<0.001

  Initial peritoneal dialysis (n, %)

     

<0.001

    CAPD

2024 (84)

703 (80)

682 (82)

397 (75)

3806 (82)

 

    APD

391 (16)

180 (20)

154 (18)

132 (25)

857 (18)

 

Era

     

<0.001

  1989–1998

472 (20)

107 (12)

113 (14)

78 (15)

770 (17)

 

  1999–2006

947 (39)

343 (39)

288 (34)

193 (37)

1771 (38)

 

  2007–2014

996 (41)

433 (49)

435 (52)

258 (49)

2122 (46)

 

Proportion receiving kidney transplantation

427 (18)

224 (25)

185 (22)

82 (16)

918 (20)

<0.001

  1. Data expressed as mean ± SD or as number (proportion). BMI – body mass index, PD – peritoneal dialysis, CAPD – continuous ambulatory peritoneal dialysis, APD – automated peritoneal dialysis, ESKD – end-stage kidney disease.
  2. ^Defined as Aboriginal and Torres Strait Islander, Maori and Pacific Islander.