Figure 2

Three-dimensional PCA-X score scatter plots of pediatric patients with and without appendicitis using (a) serum metabolomic and inflammatory mediator profiling, and (b) urine metabolomic profiling. Each plot is based on three principal components-PC1, PC2 and PC3. Red diamonds represent distribution of pediatric patients with perforated appendicitis, blue diamonds represent patients with non-perforated appendicitis, and black diamonds represent pediatric patients with non-appendicitis abdominal pain.