Figure 5 | Scientific Reports

Figure 5

From: Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes

Figure 5

Effect of UVB on TJ structure and function in in the presence of GSH in REKs. (a) Immunostaining of claudin-1, claudin-4, and occludin at 24 hours after exposure to 10 mJ/cm2 of UVB in irradiated REKs and irradiated REKs supplemented with 5 mM GSH. Bar = 50μm. (b) TEER measurements following UVB exposure (n = 3; mean ± SEM; *P < 0.05 compared to control, non-iradiated sample). (c) Permeability of 4 kDa FITC-dextran (FD4) 24 hours following UVB exposure (n = 3; mean ± SEM; *p < 0.01 compared to irradiated cells).

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