Table 1 Patient data.

From: Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery

 

Patient

Resistance to >2AEDs

Age at surgery (yrs)

Duration of epilepsy (from onset; yrs)

Seizure frequency (n/mo)

AEDs at surgery

Hippocampal pathology

CPH

1

Yes

52

25

1 (KFA)

LTG, LEV

HS

CPH

2

Yes

54

14

5 (KFA)

LEV, LTG

HS

CPH

3

Yes

41

34

8 (SFA), 5 (KFA)

ZNS, LAC, CLB

HS

Lund

4

Yes

36

35

5

LTG, VPA

HS

CPH

5

Yes

55

19

8 (SFA), 4 (KFA)

LEV, LAC

HS

CPH

6

Yes

31

12

1 (SFA), 1 (KFA)

LTG, LEV

HS

CPH

7

Yes

57

5

9 (KFA)

OXC

HS

CPH

8

Yes

34

8

3 (KFA)

CBZ, LEV, LAC

HS

Lund

9

Yes

28

16

3

LTG, LEV

Normal

CPH

10

Yes

18

12

8 (SFA), 8 (KFA)

VPA

HS

CPH

12

Yes

44

16

5

BV, ZNS, LTG

Normal

CPH

13

Yes

19

13

6 (SFA) 6 (KFA)

LEV, CBZ

HS

Lund

14

Yes

23

22

4 (KFA)

LEV, LAC

HS

CPH

15

Yes

36

26

12 (SFA), 12 (KFA)

LTG, LEV

HS

Lund

16

Yes

6

5

30

LTG, LEV

HS

  1. Seizure frequency reported by patients in Copenhagen (CPH) reported as simple focal seizures (SFS) and complex focal seizures (CFS). If SFS are not noted the patient does not report experiencing auras/SFS. Abbreviations as follows carbamazepine (CBZ), clobazam (CLB), Brivaracetam (BV), lacosamide (LAC), lamotrigine (LTG), levetiracetam (LEV), oxcarbazepine (OXC), valproate (VPA) and zonesamide (ZNS) and hippocampal sclerosis abbreviated as (HS).