Figure 1
From: Tissue Phenomics for prognostic biomarker discovery in low- and intermediate-risk prostate cancer
The Tissue Phenomics workflow. (A) General workflow: Tissue Phenomics is a Big Data approach for quantitative histopathology, spanning from assay development to phene validation based on automated multi-parametric optimization. (B) Example application: Identification of phenes for improved prognosis for low- and intermediate-risk prostate cancer patients after radical prostatectomy. Note that in this example the phene validation step is not yet fully covered. (For algorithm descriptions see supplemental material, flow charts).
