Figure 11 | Scientific Reports

Figure 11

From: Tissue Phenomics for prognostic biomarker discovery in low- and intermediate-risk prostate cancer

Figure 11

Result for uni-variate stratification with cross validation using the top-3-ranking significant phenes in Table 2. The Kaplan-Meier plots show groups “non-progression” (green) versus “progression” (blue) as predicted, with the events corresponding to true tumor progression state. X-axis: disease-free survival time (DFS) in month, y-axis: disease-free survival probability. The provided accuracies and p-values are obtained by aggregating the test set predictions in a leave-one-out cross validation. The box plots visualize the respective distributions for each phene. In the confusion matrices rows provide the true class and columns the predicted class (0: non-progression, 1: progression). (Note that for some patients with DFS times of up to 36 month the exact disease recurrence dates were not available and only the approximated DFS time of 36 month could be used, leading to the event aggregation at 36 month in the plot).

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